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Some people discover they are drinking far less water than they assumed

An animal study conducted by Koeth and colleagues found that TMAO decreases the bile acid pool size and inhibits the expressions of the key BA synthetic enzymes (Cyp7a1 and Cyp27a1) and BA transporters (Oatp1, Oatp4, Mrp2, and Ntcp) in the liver (Koeth et al., 2013)

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In AD, glutamatergic and cholinergic synapses of the temporal lobe are affected first, followed by a spread to other regions (Golde, 2006)

This is in order to keep the effects of steroids in the area where it is needed and to reduce the chance that side effects might be caused elsewhere in the body from absorption of steroids

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