Docking protein 3 (DOK3) associates with Lyn to restrict SYK activation and calcium signaling (Lsing et al, 2013
These changes in the LC levels observed in rats and mice are in agreement with the aforementioned VPA mechanism that leads to LC depletion, and the consequential increase in the AC/LC ratio reflecting mitochondrial dysfunction
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Additionally, it has been observed that broilers exposed to 2.5 ppm of AFB1 produced more total volatile fatty acids, indicating an association between higher AFB1 dose and a higher incidence of LAB in the gut (Galarza-Seeber et al., 2016)
10.1016/j.molimm.2013.04.002 Mol Immunol