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JAMA 284 , 22152221 (2000)

When to Contact Your Healthcare Provider About Side Effects Severe or worsening nausea and vomiting beyond the first two weeks, inability to keep food or water down for more than a few hours, or signs of dehydration (dizziness, dry mouth, dark urine) require immediate medical attention

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But GI symptoms can happen during the process

This lack of regulation raises concerns about product purity, dosage accuracy, and contamination with harmful substances