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6 One study of both adapalene 0.3% and tazarotene 0.1% for management of acne found significant improvement in macular acne scars in the tazarotene group

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Before supplementing, consult your doctor about appropriate dosing if you are taking a medication that impairs absorption (such as PPIs or diuretics) or if you have a condition that impairs excretion (such as kidney disease)

Possible Side Effects: Mild nausea

doi:10.1002/14651858.CD007348.pub3

So while you can supplement with glutathione directly (and sometimes should), raising NAD levels can also help your body make its own glutathione more efficiently