Whats more, the studies of brodalumab, a humanized monoclonal antibody that binds to IL-17RA, was stopped because of the relative lack of efficacy in the initial asthma clinical trial and a questionable safety issue (58)
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Trimethylamine-N-oxide aggravated the sympathetic excitation in D-galactose induced aging rats by down-regulating P2Y12 receptor in microglia
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