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[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Dong X., Li D., Liu H., Zhao Y

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However, it is well established that intracellular NAD pools are highly dynamic, as NAD serves not only as an electron donor in the ETC but also as a substrate for several enzymatic pathways, including sirtuins (SIRTs)

Discontinue use immediately if adverse reactions occur

This aggressive start is important for those with big deficiencies