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Hypoxia-activated pro-drugs (HAPs) have been a research focus for several decades
Some people continue beyond that
351 In the process of ferroptosis, cells are affected by oxidative stress and lipid peroxidation, resulting in the rupture of cell membranes and cell death, which is manifested mainly by the reduction in GPX4, the core enzyme of the antioxidant system (glutathione system), and the high expression of the lipid peroxidation marker 4-HNE
Doubling up is not supported by any published research and is not recommended
Health Hygiene 21(3):129 Trio PZ, You S, He X, He J, Sakao K, Hou D-X (2014) Chemopreventive functions and molecular mechanisms of garlic organosulfur compounds
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