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The osteoarthritis arm reflects research interest in whether weight-reduction mediated by the compound translates to mechanical-loading-related joint outcomes

Nature Metabolism, 5(6), 945-954

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That year Charles Kimball, a biochemist, and John Murlin, a physiologist, at the University of Rochester in New York, isolated a substance in the duodenal and pancreatic mucosa of dogs that raised blood sugar levels in depancreatised dogs