Depleted GSH worked together with the glutaminase inhibitor to relieve oxaliplatin efflux, resulting in remarkable anticancer efficiency in tumor cells and tissue (Figures 4E, F)
Alcohol & Smoking Both alcohol and cigarette smoke increases free radical production, leading to greater oxidative damage and a higher demand for glutathione
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Int Energy J 20:611620 Lafarga T, Snchez-Zurano A, Villar S, Morillas-Espaa A, Acin G (2021) Industrial production of spirulina as a protein source for bioactive peptide generation
The first reaction is catalyzed by -glutamylcysteine synthetase, joining L-glutamate and L-cysteine into -glutamylcysteine
Mahmoudi H et al