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This physician oversight continues throughout the journey, with dosage adjustments, guidance, and progress tracking

That is not unique to GLP-1s

The same review found that a daily oral semaglutide pill was as effective as a once-weekly 1 mg shot of semaglutide for weight loss

In reality, up to 70% of patients stop GLP-1 treatment within a year most often due to: High cost (GLP-1s can cost $1,000+ per month without insurance) Loss of insurance coverage for weight loss treatment Side effects such as nausea, diarrhea, constipation, or fatigue A Misconceptions some patients stop once they lose initial weight, believing they no longer need the medication 2

Weight loss from microdosing is likely modest and short-term, highly variable, and not guaranteedand there is still the problem of long-term maintenance if new habits are not adopted and the drug is discontinued, Zimmermann says

[6] [8] Several ongoing clinical trials are specifically examining GLP-1 receptor agonists for alcohol use disorder