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And these drugs soon may be employed to treat other conditions

Women are increasingly turning to GLP-1 medications to lose weight, especially during menopause

Caroline Glenn share their personal journeys and experiences with personalized wellness support

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On one hand, the cardiovascular protection afforded by SGLT2is seems to result from their beneficial hemodynamic effects, including improvement in ventricular preload (secondary to natriuresis and osmotic diuresis) and afterload (through blood pressure reduction), but also from improvement of cardiac metabolism (through the switch from utilization of glucose to ketones), inhibition of the myocardial Na + /H + exchanger, reduction of cardiac fibrosis and necrosis, reduction of proinflammatory adipokines derived from epicardial and perivascular fat, and stimulation of erythropoiesis (which can facilitate the release of oxygen to ischemic tissues) [1, 4, 14,15,16]

The authors also noted emerging evidence suggesting GLP-1 receptors are present in skin cells and hair follicles, raising the possibility of direct medication effects on skin biology beyond what weight loss alone would explain