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Rosenstock and colleagues examined the type 2 diabetes Phase 2 in The Lancet comparing retatrutide against placebo and an active comparator on glycemic and weight endpoints (PMID 37385280)

DSIP is a neuropeptide reference compound investigated in sleep, stress, endocrine and CNS-response research

Furthermore, this patient subgroup reported increased adverse events related to weight loss (ROR = 10.85, 95% CI 9.1212.91) and metabolic disturbances

doi: 10.1093/hmg/ddu243 255 ShengY.ChattopadhyayM.WhiteleggeJ.ValentineJ

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