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Reduced caloric intake from appetite suppression can contribute to fatigue, as can the metabolic adjustments your body makes in response to GLP-1 receptor activation

Most side effects are short-term and improve as your body adjusts, especially with gradual dose increases

Some participants quit because they felt they were losing too much weight

Key takeaways GLP-1 (glucagon-like peptide-1) is a naturally occurring hormone that helps reduce appetite, regulate blood sugar levels and slow digestion

this increases GLP-1 as well

Sleep apnea improvements Weight loss from any of these medications can improve obstructive sleep apnea