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On dermoscopy, after 3 months of treatment, some improvement was noted on right side in the form of decreased shades of pigmentary network in cases of epidermal melasma and decreased irregularity of pigmentary network, decreased number of granules and globules in cases of mixed melasma in comparison with baseline

These include hydroxyl, superoxide and nitric oxide radicals, hydrogen peroxide, singlet oxygen, hypochlorous acid (HOCl), and peroxynitrite (Figure 1)

Most of the evidence supporting BPC-157 comes from preclinical laboratory and animal research

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5.6 Role of B7-H3 in angiogenesis Several studies show that B7-H3 promotes angiogenesis