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A meta-analysis of six randomized trials that compared 3 to 6 months of postoperative treatment with a gonadotropin-releasing hormone agonist (GnRH), danazol, or combined oral contraceptives with no postoperative treatment of placebo revealed a significant reduction in pain scores at the conclusion of therapy in the active-treatment groups, although the benefits were inconsistent with longer follow-up (to 18 months) after discontinuation of therapy (22)

Sympathetic nervous system activation Beyond the direct receptor effect, semaglutide also engages the sympathetic nervous system through central GLP-1 receptor activity in the brain

The designed nanogenerator achieved efficient antibacterial activity by synergistically inducing oxidative stress and reducing bacterial membrane ATP, thereby accelerating the healing of chronic diabetic wounds (Fig

doi: 10.1002/ana.10483

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