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This particularly concerns at-risk pregnancies, where increasing evidence shows that Se deficiency may be implicated in miscarriage, preeclampsia, retarded fetus intrauterine growth, and preterm birth

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In a 2013 study by Korenevsky et al., the researchers administered a combination of melatonin and epithalon to female rats exposed to suboptimal environmental factors, such as light pollution, finding that the combined therapy rectified various impairments of the hypothalamic-pituitary-gonadal axis [13]