Tesamorelin's Phase 3 trials and Sermorelin's original approval studies were built around HIV-associated lipodystrophy and pediatric growth failure, not muscle building, so their bodybuilding use rests on extrapolation rather than direct testing
At baseline, the mean age was 62 years (range 45 to 93), 72% were male, 84% were White, 4% were Black or African American, and 8% were Asian, and 10% were Hispanic or Latino
We dont just have to increase energy production, we have to increase energy producers
Effect of MELANOTAN, [Nle4, D-Phe7]-alpha-MSH, on melanin synthesis in humans with MC1R variant alleles Peptides, 2006, melaninrespons vid MC1R-varianter PMID 12591111 Ter Laak MP et al
Overall, the study's ABPM data associated subcutaneous BMT administered at 1.25 or 1.75 mg with small, transient increases in ambulatory BP (3 mmHg in SBP and DBP, confined to the first 4 h postdose), accompanied by small (5%) decreases in heart rate
de Heer J, Rasmussen C, Coy DH, Holst JJ
