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For BPC-157, the agency cited the potential for immunogenicity, peptide-related impurities, problems characterizing the active ingredient, and a lack of safety data for the proposed routes of administration

[DOI] [PMC free article] [PubMed] [Google Scholar] Gupte P

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Petrelintide is an investigational long-acting human amylin analog being evaluated for weight management in people with overweight and obesity, including those with T2D in the ZUPREME-2 monotherapy trial

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