We first review the basic physiology of glutamatergic neurotransmission and its perturbation in the context of the NMDA-R hypofunction model
In addition, DHA induced ferroptosis as an antitumor agent in primary liver cancer (PLC) by activating the anti-survival unfolded protein response (UPR) and upregulating Chac GSH specific -glutamylcyclo-transferase 1 (CHAC1) expression, which was significantly attenuated by Fer-1 and DFO application after iron loading (95)
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