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In clinical trials, people taking Wegovy lost an average of 15% of their body weight over a year , significantly more than people taking a placebo

Coskun et al., LY3437943, a novel triple glucagon, GIP, and GLP- 1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept, Cell Metab., vol

The STEP trials, which evaluated once-weekly semaglutide for chronic weight management, showed that patients on 2.4 mg experienced average weight loss of 15% body weight over 68 weeks compared to 2.6% for placebo

This selective action makes Ipamorelin useful for studies that require growth hormone stimulation without broader hormonal effects

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