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The active ingredients in prescription weight loss medications (such as semaglutide or tirzepatide) are large protein molecules called peptides

The literature falls into four tiers

While there may be some resistance to the conduction of clinical trials of pharmacological interventions in these clinical populations, the mechanistic profile of GLP-1RAs clearly suggests that these medications may play a role in the treatment of certain specific eating disorders, such as BED

By enhancing glucose metabolism, they reduce excessive androgen production and can support improved fertility

In a filing submitted March 18, plaintiffs argue that the drug makers overstated the benefits of GLP-1 drugs while minimizing the risk of serious gastrointestinal injuries, including gastroparesis, ileus, and intestinal obstruction

Trial participants receive the study drug at no cost under close monitoring, but eligibility is narrow and slots are limited