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GLP-1RA drugs came out on top, not only controlling blood glucose but also reducing the risk of major heart-related events and the risk of death overall

The full clinical study protocol and prespecified statistical analysis plan are available in the Supplementary Information (Supplementary Notes 2 and 3)

Driver #3: Titration Speed and Treatment Duration Standard titration typically reaches maintenance doses in 12-16 weeks

Of the top 10, Novo Nordisk leads with 53 active studies, while Brigham Womens Hospital and Eli Lilly both have 8, and an assortment of research hospitals and universities round out the top 10

However, the timeframe is significantly off: Phase 2 was 48 weeks (about 11 months) and TRIUMPH-4 was 68 weeks (about 16 months), not 6 months

The authors declare no conflict of interest