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Advise patients to discontinue dapagliflozin and metformin hydrochloride extended-release tablets immediately and to promptly notify their healthcare provider if unexplained hyperventilation, myalgia, malaise, unusual somnolence, dizziness, slow or irregular heartbeat, sensation of feeling cold (especially in the extremities), or other nonspecific symptoms occur

Multiple research groups worldwide are investigating Wnt pathway modulation through various mechanisms

Liu E, Sun T, Liu C, Wang S, Wang S

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