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Intranasal delivery lets the peptide bypass the blood-brain barrier via olfactory transport routes, which speeds its central nervous system effects in animal models

Takeaway GLP-1 is a naturally occurring hormone in the human body that regulates blood sugar levels as well as reduces appetite to control body weight

GI side effects with oral semaglutide are reported at similar rates to injectable formulations, though some users report that nausea is more meal-dependent with the oral form

It converts fat stores into usable energy

In contrast, others may only require GLP-1 intermittentlyfor example, every other weekwhile still others may be able to discontinue it completely

Frequently asked questions What is the starting dose for semaglutide for weight loss