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Low bioavailability and hemolytic toxicity represent the two primary bottlenecks restricting the clinical translation of saponins

Glossary Excitatoryinhibitory balance The relative strength of excitatory and inhibitory signalling in a circuit, which together determine circuit excitability and information flow

Am J Physiol Cell Physiol 281:C1964C1970 Romera C, Hurtado O, Botella SH, Lizasoain I, Cardenas A, Fernandez-Tome P, Leza JC, Lorenzo P, Moro MA (2004) In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway

Figure S5

With respiratory mucosa as the initial site in coronavirus infection and transmission