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Abstract Atopic dermatitis (AD) is a chronic inflammatory skin disorder that affects a significant portion of the global population, severely impacting the quality of life and causing physical and psychological distress of patients

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In experimental studies, MEL also influenced autophagy processes and phosphorylation of mTOR (mammalian target of rapamicin), which is a common, highly conserved serine/threonine kinase that binds to raptor or riptor and other proteins, forming mTORC1 and mTORC2 complexes in turn (264)

Single-cell transcriptome profiling of human pancreatic islets in health and type 2 diabetes