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By L4, the quadruple mutants had made a total of 15 germ cells on average (range=12-20, n=5) (Figure 4E,F), similar to the number of germ cells estimated from adult sperm number at the same temperature (Figure 3B,C) and consistent with cell death having little impact on germ cell number

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Whereas, SIRT3 silencing suppressed CPT2 enzymatic activity in adipocytes (Fig