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Because the incidence of depressive and pain symptoms is increasing in parallel with the aging of the world population, it is particularly important to develop strategies that target both disorders to minimize polypharmacy and optimize therapeutic outcomes (Solhaug et al., 2012

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Many formulas also include prebiotics or added fiber designed to support gut bacteria activity, and some add plant-based or digestive ingredients that are marketed to support fullness, digestion, or blood sugar response

Ozempic's active ingredient, semaglutide, works by mimicking a hormone released by the intestine to stimulate insulin secretion and to slow down the movement of food from the stomach to the intestine, both of which reduces blood glucose