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The drugs effects became so intense that she claimed she was unable to keep down food or water, eventually leading to a hospital visit and a seizure caused by dehydration

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doi: 10.1007/s40265-018-1040-1

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Understanding the role of TMAO in kidney diseases may lead to the development of novel therapeutic approaches that target TMAO metabolism and signaling pathways for the prevention and treatment of kidney diseases

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Jakubowska A, le Roux CW, Viljoen A

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At twice-weekly dosing, the vial would last 10 weeks exceeding the stability window

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