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Gallbladder disorders: In the STEP 1 trial found a higher incidence of gallbladder-related events, such as gallstones or cholecystitis, was found in the semaglutide group than the placebo group

Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, et al

Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction

Eating smaller, more frequent meals, avoiding high-fat foods, and staying well-hydrated can help manage these symptoms

Drug Interactions: Oral medications: delayed gastric emptying may reduce peak plasma concentrations of oral drugs taken concomitantlytake time-sensitive oral medications (e.g., oral contraceptives, antibiotics) at a consistent time relative to semaglutide injection

Try a dance video at home or invite a friend for a brisk walk," says Dr