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The larger needle makes it easy to pierce the tough rubber stoppers without coring them

Lassailly, G

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Additionally, mitochondrial dysfunction, as a hallmark event that terminates ferroptosis and leads to ROS accumulation, has previously been reported as a critical pathogenic mechanism in IIM [227, 228]

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Chemical exchange saturation transfer (CEST) MRI, including amide proton transfer imaging, extends functional imaging capability by allowing indirect assessment of tissue pH and protein metabolism through proton exchange mechanisms (192, 193)