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Patients with certain genetic profiles may experience faster weight loss or sharper hormonal shifts, making them candidates for slower semaglutide titration or closer reproductive health monitoring

Because to structural changes that lessen its binding to insulin-like growth factor binding proteins (IGFBPs), IGF-1 LR3 has a much longer half-life than naturally occurring IGF-1

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Moradpour, Lausanne (Gastroentrologie)