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Glucomannan dosing and safety: The GB Nutrition and Health Claims Register (based on retained EFSA opinions) permits a qualified health claim for glucomannan contributing to weight loss as part of an energy-restricted diet, at a dose of 3 g per day taken in three 1 g doses before meals

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Atherosclerosis is associated with impairment of vascular endothelial function, thereby compromising vasodilation and normal blood flow

Figure 1 and Table 2 have been included to represent schematically IGF-1 actions in metabolism with target organs