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(2009) 296:E118394

Use reliable contraception while on treatment

A subset of clinical research has also demonstrated that adding B12 (and other B-vitamins) to existing antidepressant regimens can improve response rates compared to antidepressants alone, particularly when baseline B12 was suboptimal

These effects are generally not clinically significant for most medicines, but caution is advised with narrow therapeutic index drugs (e.g., warfarin, where INR monitoring may be appropriate)

22 Topical GSH-CD after three days showed elevated GSH levels in blood mononuclear cells and red blood cells along with decreased levels of the oxidative stress marker malandialdehyde