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Proinsulin-reactive CD4 T cells in the islets of type 1 diabetes organ donors

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Community protocols then increase to 0.5 mg 3x weekly (1.5 mg total weekly) when well-tolerated

Per week: 14 swabs 8 weeks: 112 swabs 2 100-count boxes 12 weeks: 168 swabs 2 100-count boxes 16 weeks: 224 swabs 3 100-count boxes Important Notes Practical points that keep administration safe and consistent

Other treatment options have traditionally included surgical removal (excision), liquid nitrogen (freezing it off), curettage (scraping it off, often with electrical controlled burning), and lasering it off

Cagrilintide acts via amylin and calcitonin receptors, while semaglutide, tirzepatide, and retatrutide target incretin (GLP-1/GIP) receptors