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Although testing in the human body has not been conducted, in vitro testing suggests that Lactobacillus fermentum ME-3 may be able to tolerate exposure to harsh acidity in the stomach and exposure to bile acids in the small intestine

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In the MRL/lpr lupus mouse model, butyrate supplementation reverses SLE-related gut microbiota dysbiosis and protects against renal damage (154)

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