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Average weight loss is 15-20% of body weight over 6-12 months
The Bottom Line Travelling with GLP-1 medications may require a little preparation, but it is usually manageable
Who Should Consider GLP-1 Antagonists
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These effects are seen even outside of diabetes control.[ref] Decreased colon cancer mortality: A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)
For appetite suppression and weight loss, the timeline differs somewhat
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