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PDHC links cytosolic glycolysis to the mitochondrial TCA cycle by oxidizing pyruvate, the end product of glycolysis

The question that researchers, clinicians, and patients are increasingly asking is not whether BPC-157 does something, but what the right BPC-157 dosage and protocol looks like for a given purpose

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It was withdrawn in 2010 for causing severe liver toxicity due to an unstable N -acylhydrazone linker 13

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10.1016/j.biomaterials.2020.120555 197 PengH.OuA.HuangX.WangC.WangL.YuT.et al (2021b)