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In the context of BD, small-scale studies and case series have demonstrated that GLP-1 RAs such as liraglutide and semaglutide may mitigate antipsychotic-induced weight gain and metabolic dysregulation, particularly in PlwBD resistant to lifestyle interventions or metformin therapy (81, 82, 84, 85)

Clin Pharmacokinet 60:10491059

Tirzepatide, also known as LY3298176 or P1206, is a synthetic dual receptortargeted peptide supplied as a high-purity lyophilized powder for laboratory research

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We used ultracentrifugation to determine the relative solubilities of the GLP-1 variants (Table 3)

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